A Case Report: Ruptured Testicular Seminoma in a Female with Ambiguous Genitalia, Dr. Sulman Alamin Medical Center, Elhassaheisa, Gezira State, Sudan; 2023

Khalid Adam Babiker Suleiman; Omer Taha Ahmed Elmukashfi; Taha Ahmed Elmukashfi Elshiekh; Asma Mohammed Warrag Omer

doi:doi:10.11648/j.ijmcr.20230202.12

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A Case Report: Ruptured Testicular Seminoma in a Female with Ambiguous Genitalia, Dr. Sulman Alamin Medical Center, Elhassaheisa, Gezira State, Sudan; 2023

Khalid Adam Babiker Suleiman, Omer Taha Ahmed Elmukashfi, Taha Ahmed Elmukashfi Elshiekh, Asma Mohammed Warrag Omer

Published in International Journal of Medical Case Reports (Volume 2, Issue 2)

Received: 13 March 2023 Accepted: 12 May 2023 Published: 25 May 2023

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Abstract

Background: Ambiguous genitalia represent a sequel of sexual development disorders where the external genitalia don’t have a typical resemblance to that of male or female. Methods: This was a female case of ambiguous genitalia, her age was twenty-eight years, ultrasound examination revealed atrophied uterus and bilateral undescended testes. She complained of gradual size increase of her left testicle in the last 6 months. Due to sudden trauma, she developed severe pain and swelling in her left groin. On examination: patient looked unwell, in pain, afebrile, locally there was swelling about 10 cm in size with shiny and red looking, it was very tender, otherwise it was unremarkable. So, this was considered as a case of left testicular trauma that need urgent left groin exploration. The patient was counselled and consented about possible orchidectomy. Intra-operative note: under spinal anesthesia patient was put on supine position, skin painted by yamidin, left inguinal incision was made and hematoma was evacuated, the left testicle was found to be hugely enlarged and ruptured. The spermatic cord was clamped and orchidectomy was done. No intra operative complications. Result: Histological examination of the testicular specimen confirmed that it was a germ cell tumor [Seminoma]. Patient was recommended to for: (1) Chemotherapy at the Oncology Department, (2) Laparoscopic search for her right undescended testis to confirm whether it is a testis or an ovary, (3) Buccal biopsy for sex determination and (4) Surgery, for the right side, if needed. Conclusion and recommendation: Neglected cases of undescended testis may have a serious outcome. Screening for ambiguous genitalia, and early exploration and management was highly recommended.

Published in	International Journal of Medical Case Reports (Volume 2, Issue 2)
DOI	10.11648/j.ijmcr.20230202.12
Page(s)	12-15
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2023. Published by Science Publishing Group

Keywords

Ambiguous Genitalia, Testicular Seminoma, Sudan

References

[1]	Manzoor J, Aftab S and Yaqoob M, Ambiguous genitalia: An overview of 7 years’ experience at the Children’s Hospital & Institute of Child Health, Lahore, Pakistan, Pak J Med Sci January - February 2019, 35 (1), pp: (151-155).
[2]	Gentile M N, Lam L, Gangat M and Kogeman Y, An unusual case of ambiguous genitalia, IJCRI 2012, 3 (3), pp: (24-26).
[3]	Chowdhury M A K, Anwar R and Saha A, Ambiguous genitalia–A social dilemma in Bangladesh: A case report, International Journal of Surgery Case Reports 42 (2018), pp: (98–101).
[4]	Coşkun A, Özdemir Ö, Akdemir G, Kirank G, Antenatal Diagnosis of Ambiguous Genitalia in a Fetus at 28th Gestational Week, Gynecol Obstet Reprod Med, 13 (2), pp: (174-175).
[5]	Sabnis A, Kamale V N, Ambiguous Genitalia: A Case Report, International Journal of Science and Research, 7 (4), April 2018, pp: (114-116).
[6]	Luz C C, et al, Cases of ambiguous genitalia from a public university hospital, Residência Pediátrica; 2022: Ahead of Print, pp: (1-5).
[7]	Sheikh W H, et al, A Child with Ambiguous Genitalia: An Atypical Presentation, Journal of the College of Physicians and Surgeons Pakistan 2019, Vol. 29 (Special Supplement 1 of Case Reports), pp: (S54-S55).
[8]	Aliyu I, Microcephaly with ambiguous genitalia, Medical Journal of Dr. D. Y. Patil University, November-December 2015, 8 (6), pp: (766-768).
[9]	Paula G B D, et al, 408 Cases of Genital Ambiguity Followed by Single Multidisciplinary Team during 23 Years: Etiologic Diagnosis and Sex of Rearing, International Journal of Endocrinology Volume 2016, Article ID 4963574, 9 pages.
[10]	Elshimy G, Tran K, Harman S M, and Ricardo Correa R, Unmasked Testicular Seminoma During Use of Hormonal Transgender Woman Therapy: A Hidden hCG-Secreting Tumor, Journal of the Endocrine Society, July 2020, 4 (7), PP: (1-8).
[11]	Sowande O A, Adejuyigbe O, Management of ambiguous genitalia in ile ife, Nigeria: Challenges and outcome, African Journal of Paediatric Surgery, January-June 2009. 6 (1), PP: (14-18).
[12]	Sato T, et al, Less-Invasive Diagnostic Approaches for Infants with Suspected Differences of Sex Development: A Case Report of a 297-g Neonate with Ambiguous Genitalia, Neonatology 2022, 119, PP: (785–789).
[13]	Gargari S S, Azizi F, Saleh N, Omrani M D, A Case with late onset of ambiguous genitalia, Int J Reprod BioMed, 15 (3). pp: (175-178).
[14]	Mil E and Hiort O, Three out of four: a case discussion on ambiguous genitalia, European Journal of Endocrinology 2008, 159, PP: (S91–S93).
[15]	Ng S F, Boo N Y, Wu L L, Shuib S, A rare case of ambiguous genitalia, Singapore Med J 2007; 48 (9), PP; (858-861).

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Khalid Adam Babiker Suleiman, Omer Taha Ahmed Elmukashfi, Taha Ahmed Elmukashfi Elshiekh, Asma Mohammed Warrag Omer. (2023). A Case Report: Ruptured Testicular Seminoma in a Female with Ambiguous Genitalia, Dr. Sulman Alamin Medical Center, Elhassaheisa, Gezira State, Sudan; 2023. International Journal of Medical Case Reports, 2(2), 12-15. https://doi.org/10.11648/j.ijmcr.20230202.12

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ACS Style

Khalid Adam Babiker Suleiman; Omer Taha Ahmed Elmukashfi; Taha Ahmed Elmukashfi Elshiekh; Asma Mohammed Warrag Omer. A Case Report: Ruptured Testicular Seminoma in a Female with Ambiguous Genitalia, Dr. Sulman Alamin Medical Center, Elhassaheisa, Gezira State, Sudan; 2023. Int. J. Med. Case Rep. 2023, 2(2), 12-15. doi: 10.11648/j.ijmcr.20230202.12

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AMA Style

Khalid Adam Babiker Suleiman, Omer Taha Ahmed Elmukashfi, Taha Ahmed Elmukashfi Elshiekh, Asma Mohammed Warrag Omer. A Case Report: Ruptured Testicular Seminoma in a Female with Ambiguous Genitalia, Dr. Sulman Alamin Medical Center, Elhassaheisa, Gezira State, Sudan; 2023. Int J Med Case Rep. 2023;2(2):12-15. doi: 10.11648/j.ijmcr.20230202.12

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@article{10.11648/j.ijmcr.20230202.12,
  author = {Khalid Adam Babiker Suleiman and Omer Taha Ahmed Elmukashfi and Taha Ahmed Elmukashfi Elshiekh and Asma Mohammed Warrag Omer},
  title = {A Case Report: Ruptured Testicular Seminoma in a Female with Ambiguous Genitalia, Dr. Sulman Alamin Medical Center, Elhassaheisa, Gezira State, Sudan; 2023},
  journal = {International Journal of Medical Case Reports},
  volume = {2},
  number = {2},
  pages = {12-15},
  doi = {10.11648/j.ijmcr.20230202.12},
  url = {https://doi.org/10.11648/j.ijmcr.20230202.12},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijmcr.20230202.12},
  abstract = {Background: Ambiguous genitalia represent a sequel of sexual development disorders where the external genitalia don’t have a typical resemblance to that of male or female. Methods: This was a female case of ambiguous genitalia, her age was twenty-eight years, ultrasound examination revealed atrophied uterus and bilateral undescended testes. She complained of gradual size increase of her left testicle in the last 6 months. Due to sudden trauma, she developed severe pain and swelling in her left groin. On examination: patient looked unwell, in pain, afebrile, locally there was swelling about 10 cm in size with shiny and red looking, it was very tender, otherwise it was unremarkable. So, this was considered as a case of left testicular trauma that need urgent left groin exploration. The patient was counselled and consented about possible orchidectomy. Intra-operative note: under spinal anesthesia patient was put on supine position, skin painted by yamidin, left inguinal incision was made and hematoma was evacuated, the left testicle was found to be hugely enlarged and ruptured. The spermatic cord was clamped and orchidectomy was done. No intra operative complications. Result: Histological examination of the testicular specimen confirmed that it was a germ cell tumor [Seminoma]. Patient was recommended to for: (1) Chemotherapy at the Oncology Department, (2) Laparoscopic search for her right undescended testis to confirm whether it is a testis or an ovary, (3) Buccal biopsy for sex determination and (4) Surgery, for the right side, if needed. Conclusion and recommendation: Neglected cases of undescended testis may have a serious outcome. Screening for ambiguous genitalia, and early exploration and management was highly recommended.},
 year = {2023}
}

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TY - JOUR
T1 - A Case Report: Ruptured Testicular Seminoma in a Female with Ambiguous Genitalia, Dr. Sulman Alamin Medical Center, Elhassaheisa, Gezira State, Sudan; 2023
AU - Khalid Adam Babiker Suleiman
AU - Omer Taha Ahmed Elmukashfi
AU - Taha Ahmed Elmukashfi Elshiekh
AU - Asma Mohammed Warrag Omer
Y1 - 2023/05/25
PY - 2023
N1 - https://doi.org/10.11648/j.ijmcr.20230202.12
DO - 10.11648/j.ijmcr.20230202.12
T2 - International Journal of Medical Case Reports
JF - International Journal of Medical Case Reports
JO - International Journal of Medical Case Reports
SP - 12
EP - 15
PB - Science Publishing Group
SN - 2994-7049
UR - https://doi.org/10.11648/j.ijmcr.20230202.12
AB - Background: Ambiguous genitalia represent a sequel of sexual development disorders where the external genitalia don’t have a typical resemblance to that of male or female. Methods: This was a female case of ambiguous genitalia, her age was twenty-eight years, ultrasound examination revealed atrophied uterus and bilateral undescended testes. She complained of gradual size increase of her left testicle in the last 6 months. Due to sudden trauma, she developed severe pain and swelling in her left groin. On examination: patient looked unwell, in pain, afebrile, locally there was swelling about 10 cm in size with shiny and red looking, it was very tender, otherwise it was unremarkable. So, this was considered as a case of left testicular trauma that need urgent left groin exploration. The patient was counselled and consented about possible orchidectomy. Intra-operative note: under spinal anesthesia patient was put on supine position, skin painted by yamidin, left inguinal incision was made and hematoma was evacuated, the left testicle was found to be hugely enlarged and ruptured. The spermatic cord was clamped and orchidectomy was done. No intra operative complications. Result: Histological examination of the testicular specimen confirmed that it was a germ cell tumor [Seminoma]. Patient was recommended to for: (1) Chemotherapy at the Oncology Department, (2) Laparoscopic search for her right undescended testis to confirm whether it is a testis or an ovary, (3) Buccal biopsy for sex determination and (4) Surgery, for the right side, if needed. Conclusion and recommendation: Neglected cases of undescended testis may have a serious outcome. Screening for ambiguous genitalia, and early exploration and management was highly recommended.
VL - 2
IS - 2
ER -

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Author Information

Khalid Adam Babiker Suleiman

Hassaheisa Teaching Hospital, Ministry of Health, Elhassaheisa, Sudan
Omer Taha Ahmed Elmukashfi

General Surgery Council, Sudan Medical Specialization Board, Khartoum, Sudan
Taha Ahmed Elmukashfi Elshiekh

Department of Community Medicine, Faculty of Medicine, University of Khartoum, Khartoum, Sudan
Asma Mohammed Warrag Omer

National Cancer Institute (NCI), University of Gezira, Wadmadeni, Sudan

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APA Style

Khalid Adam Babiker Suleiman, Omer Taha Ahmed Elmukashfi, Taha Ahmed Elmukashfi Elshiekh, Asma Mohammed Warrag Omer. (2023). A Case Report: Ruptured Testicular Seminoma in a Female with Ambiguous Genitalia, Dr. Sulman Alamin Medical Center, Elhassaheisa, Gezira State, Sudan; 2023. International Journal of Medical Case Reports, 2(2), 12-15. https://doi.org/10.11648/j.ijmcr.20230202.12

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ACS Style

Khalid Adam Babiker Suleiman; Omer Taha Ahmed Elmukashfi; Taha Ahmed Elmukashfi Elshiekh; Asma Mohammed Warrag Omer. A Case Report: Ruptured Testicular Seminoma in a Female with Ambiguous Genitalia, Dr. Sulman Alamin Medical Center, Elhassaheisa, Gezira State, Sudan; 2023. Int. J. Med. Case Rep. 2023, 2(2), 12-15. doi: 10.11648/j.ijmcr.20230202.12

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AMA Style

Khalid Adam Babiker Suleiman, Omer Taha Ahmed Elmukashfi, Taha Ahmed Elmukashfi Elshiekh, Asma Mohammed Warrag Omer. A Case Report: Ruptured Testicular Seminoma in a Female with Ambiguous Genitalia, Dr. Sulman Alamin Medical Center, Elhassaheisa, Gezira State, Sudan; 2023. Int J Med Case Rep. 2023;2(2):12-15. doi: 10.11648/j.ijmcr.20230202.12

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@article{10.11648/j.ijmcr.20230202.12,
  author = {Khalid Adam Babiker Suleiman and Omer Taha Ahmed Elmukashfi and Taha Ahmed Elmukashfi Elshiekh and Asma Mohammed Warrag Omer},
  title = {A Case Report: Ruptured Testicular Seminoma in a Female with Ambiguous Genitalia, Dr. Sulman Alamin Medical Center, Elhassaheisa, Gezira State, Sudan; 2023},
  journal = {International Journal of Medical Case Reports},
  volume = {2},
  number = {2},
  pages = {12-15},
  doi = {10.11648/j.ijmcr.20230202.12},
  url = {https://doi.org/10.11648/j.ijmcr.20230202.12},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijmcr.20230202.12},
  abstract = {Background: Ambiguous genitalia represent a sequel of sexual development disorders where the external genitalia don’t have a typical resemblance to that of male or female. Methods: This was a female case of ambiguous genitalia, her age was twenty-eight years, ultrasound examination revealed atrophied uterus and bilateral undescended testes. She complained of gradual size increase of her left testicle in the last 6 months. Due to sudden trauma, she developed severe pain and swelling in her left groin. On examination: patient looked unwell, in pain, afebrile, locally there was swelling about 10 cm in size with shiny and red looking, it was very tender, otherwise it was unremarkable. So, this was considered as a case of left testicular trauma that need urgent left groin exploration. The patient was counselled and consented about possible orchidectomy. Intra-operative note: under spinal anesthesia patient was put on supine position, skin painted by yamidin, left inguinal incision was made and hematoma was evacuated, the left testicle was found to be hugely enlarged and ruptured. The spermatic cord was clamped and orchidectomy was done. No intra operative complications. Result: Histological examination of the testicular specimen confirmed that it was a germ cell tumor [Seminoma]. Patient was recommended to for: (1) Chemotherapy at the Oncology Department, (2) Laparoscopic search for her right undescended testis to confirm whether it is a testis or an ovary, (3) Buccal biopsy for sex determination and (4) Surgery, for the right side, if needed. Conclusion and recommendation: Neglected cases of undescended testis may have a serious outcome. Screening for ambiguous genitalia, and early exploration and management was highly recommended.},
 year = {2023}
}

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