Cutaneous Kaposi Sarcoma Indicative of HIV/AIDS Infection: Two Cases Report and Review of the Literature at Regional Hospital Centre of Niamey (Niger)

Kadri Sani; Harouna Amadou Mahaman Laouali; Djibrilla Almoustapha Amadou; Garba Abdoul Azize; Salifou Ibrahim Alkassoum; Daou Mamane

doi:doi:10.11648/j.ijmcr.20230204.11

Case Report |

Cutaneous Kaposi Sarcoma Indicative of HIV/AIDS Infection: Two Cases Report and Review of the Literature at Regional Hospital Centre of Niamey (Niger)

Kadri Sani, Harouna Amadou Mahaman Laouali, Djibrilla Almoustapha Amadou, Garba Abdoul Azize, Salifou Ibrahim Alkassoum, Daou Mamane

Published in International Journal of Medical Case Reports (Volume 2, Issue 4)

Received: 25 October 2023 Accepted: 21 November 2023 Published: 29 November 2023

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Abstract

Kaposi sarcoma (KS), first described in 1872 by the dermatologist Moricz Cohen Kaposi, is the most common neoplasm of people living with HIV today. Kaposi Sarcoma remains the most common cancer in people living with HIV in sub-Saharan Africa, where it causes significant morbidity and mortality. We report the case of two patients from Niger, aged 43 and 65 years old, who consulted unit of HIV care the Niamey Regional Hospital for an exploration of skin lesions in a context of altered general condition including significant weight loss. The clinical diagnosis of Kaposi's disease on a background of HIV immunodeficiency was retained. The clinical lesions were infiltrating cuteneous bluish nodular skin lesions with macules located on the legs, forearm and abdomen. The treatment consisted in putting the patients on high antiretroviral treatment followed by courses of chemotherapy. The combination of high antiretroviral therapy was started with TDF-3TC-EFV one tablet daily at bedtime. These study show the clinical polymorphism, the diagnostic delay and the treatment including polychemotherapy and antiretroviral drugs. Early diagnosis and detection of lesions could improve management and the prognosis of this disease.

Published in	International Journal of Medical Case Reports (Volume 2, Issue 4)
DOI	10.11648/j.ijmcr.20230204.11
Page(s)	24-27
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2024. Published by Science Publishing Group

Keywords

Cutaneous Kaposi's Disease, HIV/AIDS Disease, ART CHR/Niamey Niger

References

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[2]	B. Saka, A. Mouhari-Toure, I. M. Wateba, S. Akakpo, K. Kombaté, A. Balaka, A. Sogan, K. O. Afolabi, P. Pitché, K Tchangaï-Walla, Maladie de Kaposi associée au VIH: 103 observations en dermatologie à Lomé (Togo). Médecine et santé tropicale, Janvier-Février-Mars 2013 Volume 23, numéro 1.
[3]	Ndiaye Maodo, Diop Assane, Berthe Siritio, Diallo Moussa, Mjahed Sara Diatta Boubacar Ahy, Diadie Saer, Seck Ndeye Bougoul, Diallo Salimatou, Ndiaye Mame Tene, Niang Suzanne Oumou, Ly Fatimata, Dieng Mame Thierno, Kane Assane, MALADIE DE KAPOSI ENDEMIQUE A DAKAR: ETUDE DE 29 CAS.
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[5]	Mouna Lamchahab, Bouchra Oukkache, Sofia Marouan, Asmae Quessar, Said Benchekroun, Maladie de kaposi compliquant une aplasie médullaire Pan Afr Med J. 2014; 18: 169.
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[11]	Shehzeen Fatima Memon_, Anosh Aslam Khan_, Yasir Ahmad Khan_ and Hafsa Mahmood. Classic Kaposi’s Sarcoma in an exclusively cutaneous exhibition. International Journal of Medical Reviews and Case Reports (2019) 3 (9): 620-623.
[12]	David Sandoval Sanchez, Estanislao Antonio Calixto, Roberto Peralta Juárez, Marcos, García Aranda, Rolando Castellanos Villalobos, Jessica Ariatna Carreto Navarrete. Extensive Kaposi's sarcoma in a Patient with Acquired Immunodeficiency Syndrome: Case International. Journal of Medical Science and Clinical Research Studies, Report Volume 03 Issue 01 Janaury 2023 Page No: 68-70. DOI: https://doi.org/10.47191/ijmscrs/v3-i1-14
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APA Style

Sani, K., Amadou Mahaman Laouali, H., Almoustapha Amadou, D., Abdoul Azize, G., Ibrahim Alkassoum, S., et al. (2023). Cutaneous Kaposi Sarcoma Indicative of HIV/AIDS Infection: Two Cases Report and Review of the Literature at Regional Hospital Centre of Niamey (Niger). International Journal of Medical Case Reports, 2(4), 24-27. https://doi.org/10.11648/j.ijmcr.20230204.11

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ACS Style

Sani, K.; Amadou Mahaman Laouali, H.; Almoustapha Amadou, D.; Abdoul Azize, G.; Ibrahim Alkassoum, S., et al. Cutaneous Kaposi Sarcoma Indicative of HIV/AIDS Infection: Two Cases Report and Review of the Literature at Regional Hospital Centre of Niamey (Niger). Int. J. Med. Case Rep. 2023, 2(4), 24-27. doi: 10.11648/j.ijmcr.20230204.11

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AMA Style

Sani K, Amadou Mahaman Laouali H, Almoustapha Amadou D, Abdoul Azize G, Ibrahim Alkassoum S, et al. Cutaneous Kaposi Sarcoma Indicative of HIV/AIDS Infection: Two Cases Report and Review of the Literature at Regional Hospital Centre of Niamey (Niger). Int J Med Case Rep. 2023;2(4):24-27. doi: 10.11648/j.ijmcr.20230204.11

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@article{10.11648/j.ijmcr.20230204.11,
  author = {Kadri Sani and Harouna Amadou Mahaman Laouali and Djibrilla Almoustapha Amadou and Garba Abdoul Azize and Salifou Ibrahim Alkassoum and Daou Mamane},
  title = {Cutaneous Kaposi Sarcoma Indicative of HIV/AIDS Infection: Two Cases Report and Review of the Literature at Regional Hospital Centre of Niamey (Niger)},
  journal = {International Journal of Medical Case Reports},
  volume = {2},
  number = {4},
  pages = {24-27},
  doi = {10.11648/j.ijmcr.20230204.11},
  url = {https://doi.org/10.11648/j.ijmcr.20230204.11},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijmcr.20230204.11},
  abstract = {Kaposi sarcoma (KS), first described in 1872 by the dermatologist Moricz Cohen Kaposi, is the most common neoplasm of people living with HIV today. Kaposi Sarcoma remains the most common cancer in people living with HIV in sub-Saharan Africa, where it causes significant morbidity and mortality. We report the case of two patients from Niger, aged 43 and 65 years old, who consulted unit of HIV care the Niamey Regional Hospital for an exploration of skin lesions in a context of altered general condition including significant weight loss. The clinical diagnosis of Kaposi's disease on a background of HIV immunodeficiency was retained. The clinical lesions were infiltrating cuteneous bluish nodular skin lesions with macules located on the legs, forearm and abdomen. The treatment consisted in putting the patients on high antiretroviral treatment followed by courses of chemotherapy. The combination of high antiretroviral therapy was started with TDF-3TC-EFV one tablet daily at bedtime. These study show the clinical polymorphism, the diagnostic delay and the treatment including polychemotherapy and antiretroviral drugs. Early diagnosis and detection of lesions could improve management and the prognosis of this disease.
},
 year = {2023}
}

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TY  - JOUR
T1  - Cutaneous Kaposi Sarcoma Indicative of HIV/AIDS Infection: Two Cases Report and Review of the Literature at Regional Hospital Centre of Niamey (Niger)
AU  - Kadri Sani
AU  - Harouna Amadou Mahaman Laouali
AU  - Djibrilla Almoustapha Amadou
AU  - Garba Abdoul Azize
AU  - Salifou Ibrahim Alkassoum
AU  - Daou Mamane
Y1  - 2023/11/29
PY  - 2023
N1  - https://doi.org/10.11648/j.ijmcr.20230204.11
DO  - 10.11648/j.ijmcr.20230204.11
T2  - International Journal of Medical Case Reports
JF  - International Journal of Medical Case Reports
JO  - International Journal of Medical Case Reports
SP  - 24
EP  - 27
PB  - Science Publishing Group
SN  - 2994-7049
UR  - https://doi.org/10.11648/j.ijmcr.20230204.11
AB  - Kaposi sarcoma (KS), first described in 1872 by the dermatologist Moricz Cohen Kaposi, is the most common neoplasm of people living with HIV today. Kaposi Sarcoma remains the most common cancer in people living with HIV in sub-Saharan Africa, where it causes significant morbidity and mortality. We report the case of two patients from Niger, aged 43 and 65 years old, who consulted unit of HIV care the Niamey Regional Hospital for an exploration of skin lesions in a context of altered general condition including significant weight loss. The clinical diagnosis of Kaposi's disease on a background of HIV immunodeficiency was retained. The clinical lesions were infiltrating cuteneous bluish nodular skin lesions with macules located on the legs, forearm and abdomen. The treatment consisted in putting the patients on high antiretroviral treatment followed by courses of chemotherapy. The combination of high antiretroviral therapy was started with TDF-3TC-EFV one tablet daily at bedtime. These study show the clinical polymorphism, the diagnostic delay and the treatment including polychemotherapy and antiretroviral drugs. Early diagnosis and detection of lesions could improve management and the prognosis of this disease.

VL  - 2
IS  - 4
ER  -

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Author Information

Kadri Sani

Internal Medicine Unit, Regional Hospital Centre of Niamey, Niamey, Niger

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Harouna Amadou Mahaman Laouali

Infectious Diseases Unit, Faculty of Health Sciences, Dan Dicko Dan Koulodo University, Maradi, Niger

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Djibrilla Almoustapha Amadou

Internal Medicine Unit, Faculty of Health Sciences, ABDOU Moumouni Niamey University, Niamey, Niger
Garba Abdoul Azize

Internal Medicine Unit, Zinder National Hospital, Faculty of Health Sciences, University of Zinder, Zinder, Niger
Salifou Ibrahim Alkassoum

Internal Medicine Unit, Faculty of Health Sciences, ABDOU Moumouni Niamey University, Niamey, Niger
Daou Mamane

Internal Medicine Unit, Faculty of Health Sciences, ABDOU Moumouni Niamey University, Niamey, Niger

Contact Email

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Plain Text BibTeX RIS

APA Style

Sani, K., Amadou Mahaman Laouali, H., Almoustapha Amadou, D., Abdoul Azize, G., Ibrahim Alkassoum, S., et al. (2023). Cutaneous Kaposi Sarcoma Indicative of HIV/AIDS Infection: Two Cases Report and Review of the Literature at Regional Hospital Centre of Niamey (Niger). International Journal of Medical Case Reports, 2(4), 24-27. https://doi.org/10.11648/j.ijmcr.20230204.11

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ACS Style

Sani, K.; Amadou Mahaman Laouali, H.; Almoustapha Amadou, D.; Abdoul Azize, G.; Ibrahim Alkassoum, S., et al. Cutaneous Kaposi Sarcoma Indicative of HIV/AIDS Infection: Two Cases Report and Review of the Literature at Regional Hospital Centre of Niamey (Niger). Int. J. Med. Case Rep. 2023, 2(4), 24-27. doi: 10.11648/j.ijmcr.20230204.11

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AMA Style

Sani K, Amadou Mahaman Laouali H, Almoustapha Amadou D, Abdoul Azize G, Ibrahim Alkassoum S, et al. Cutaneous Kaposi Sarcoma Indicative of HIV/AIDS Infection: Two Cases Report and Review of the Literature at Regional Hospital Centre of Niamey (Niger). Int J Med Case Rep. 2023;2(4):24-27. doi: 10.11648/j.ijmcr.20230204.11

Copy | Download

@article{10.11648/j.ijmcr.20230204.11,
  author = {Kadri Sani and Harouna Amadou Mahaman Laouali and Djibrilla Almoustapha Amadou and Garba Abdoul Azize and Salifou Ibrahim Alkassoum and Daou Mamane},
  title = {Cutaneous Kaposi Sarcoma Indicative of HIV/AIDS Infection: Two Cases Report and Review of the Literature at Regional Hospital Centre of Niamey (Niger)},
  journal = {International Journal of Medical Case Reports},
  volume = {2},
  number = {4},
  pages = {24-27},
  doi = {10.11648/j.ijmcr.20230204.11},
  url = {https://doi.org/10.11648/j.ijmcr.20230204.11},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijmcr.20230204.11},
  abstract = {Kaposi sarcoma (KS), first described in 1872 by the dermatologist Moricz Cohen Kaposi, is the most common neoplasm of people living with HIV today. Kaposi Sarcoma remains the most common cancer in people living with HIV in sub-Saharan Africa, where it causes significant morbidity and mortality. We report the case of two patients from Niger, aged 43 and 65 years old, who consulted unit of HIV care the Niamey Regional Hospital for an exploration of skin lesions in a context of altered general condition including significant weight loss. The clinical diagnosis of Kaposi's disease on a background of HIV immunodeficiency was retained. The clinical lesions were infiltrating cuteneous bluish nodular skin lesions with macules located on the legs, forearm and abdomen. The treatment consisted in putting the patients on high antiretroviral treatment followed by courses of chemotherapy. The combination of high antiretroviral therapy was started with TDF-3TC-EFV one tablet daily at bedtime. These study show the clinical polymorphism, the diagnostic delay and the treatment including polychemotherapy and antiretroviral drugs. Early diagnosis and detection of lesions could improve management and the prognosis of this disease.
},
 year = {2023}
}

Copy | Download

TY  - JOUR
T1  - Cutaneous Kaposi Sarcoma Indicative of HIV/AIDS Infection: Two Cases Report and Review of the Literature at Regional Hospital Centre of Niamey (Niger)
AU  - Kadri Sani
AU  - Harouna Amadou Mahaman Laouali
AU  - Djibrilla Almoustapha Amadou
AU  - Garba Abdoul Azize
AU  - Salifou Ibrahim Alkassoum
AU  - Daou Mamane
Y1  - 2023/11/29
PY  - 2023
N1  - https://doi.org/10.11648/j.ijmcr.20230204.11
DO  - 10.11648/j.ijmcr.20230204.11
T2  - International Journal of Medical Case Reports
JF  - International Journal of Medical Case Reports
JO  - International Journal of Medical Case Reports
SP  - 24
EP  - 27
PB  - Science Publishing Group
SN  - 2994-7049
UR  - https://doi.org/10.11648/j.ijmcr.20230204.11
AB  - Kaposi sarcoma (KS), first described in 1872 by the dermatologist Moricz Cohen Kaposi, is the most common neoplasm of people living with HIV today. Kaposi Sarcoma remains the most common cancer in people living with HIV in sub-Saharan Africa, where it causes significant morbidity and mortality. We report the case of two patients from Niger, aged 43 and 65 years old, who consulted unit of HIV care the Niamey Regional Hospital for an exploration of skin lesions in a context of altered general condition including significant weight loss. The clinical diagnosis of Kaposi's disease on a background of HIV immunodeficiency was retained. The clinical lesions were infiltrating cuteneous bluish nodular skin lesions with macules located on the legs, forearm and abdomen. The treatment consisted in putting the patients on high antiretroviral treatment followed by courses of chemotherapy. The combination of high antiretroviral therapy was started with TDF-3TC-EFV one tablet daily at bedtime. These study show the clinical polymorphism, the diagnostic delay and the treatment including polychemotherapy and antiretroviral drugs. Early diagnosis and detection of lesions could improve management and the prognosis of this disease.

VL  - 2
IS  - 4
ER  -

Copy | Download